Tesamorelin & Ipamorelin
Tesamorelin and Ipamorelin are both peptides that stimulate the body’s natural production of growth hormone (GH). Rather than introducing synthetic GH into the body, these peptides signal your own glands to produce and release more of it—helping to restore more youthful hormone levels and support overall wellness.
Tesamorelin is an FDA-approved GHRH analog originally developed to treat excess abdominal fat in HIV patients with lipodystrophy.
Ipamorelin is a selective growth hormone secretagogue that mimics ghrelin to safely and gently increase GH release with minimal side effects.
When used together, these peptides work synergistically to enhance fat metabolism, support lean muscle mass, and promote recovery—without overstimulating other hormone systems.
Why Combine Tesamorelin + Ipamorelin?
Combining these two peptides offers enhanced effects compared to using either one alone.
Benefits:
🔥 Fat Loss
Targets visceral (abdominal) fat, boosts metabolism
💪 Muscle Support
Helps preserve or build lean muscle mass
🛌 Better Recovery
Improves tissue repair, joint healing, and post-exercise recovery
😴 Improved Sleep
May enhance deep, restorative sleep, when GH release is highest
💡 Anti-Aging Effects
Supports healthier skin, cognitive function, and energy levels
🧠 Brain & Metabolic Health
Potential benefits in insulin sensitivity and cognitive aging (under study)
How Are They Taken?
Route: Subcutaneous injection (under the skin)
Frequency: Typically once daily at night, or as directed by your provider
Duration: Often prescribed in 8–12 week cycles, with regular follow-up
Are Tesamorelin and Ipamorelin Safe?
Both peptides have been studied and used in clinical and wellness settings, with generally good safety profiles when prescribed appropriately.
Possible Side Effects (usually mild):
Redness or irritation at injection site
Temporary headache or nausea
Mild bloating or water retention
Tingling in hands or feet
Increased hunger or fatigue early in therapy
Who Should Not Use These Peptides:
People with active cancer or untreated tumors
Pregnant or breastfeeding individuals
Those with uncontrolled diabetes or thyroid disorders (unless cleared by a provider)
What to expect:
Week 1–4: Improved sleep, energy, and slight reduction in appetite or cravings
Week 4–8: Body composition changes begin—less belly fat, improved muscle tone
Week 8–12+: Enhanced recovery, skin health, and long-term metabolic benefits
Results vary based on age, activity level, nutrition, and baseline hormone status.
